[PConlie News] Recently, at the Collegiate Inventors Competition in the United States, the "eye-on-a-chip" technology brought by the University of Pennsylvania team has caused a lot of The attention, although the first prize of the competition was obtained by Harvard's 3D bioprinting vascularized human tissue. The so-called "eye-on-a-chip" refers to the researchers' use of chip technology to simulate the function of the human eye. In this tiny plastic chip contains multiple microfluidic channels that have been carefully designed to make the cornea cells It can grow like a human body.
Students also added a click-driven 3D print eyelid to blink like the human eye.
According to the research team's website on its school, they can simulate the human environment through these microfluidic channels and stimulate cell growth. They say that the same principle can be applied to different organs in the human body. It was designed by a team of graduate students Cassidy Blundell, Nicholas Perkons, and Jeongyun Seo of the School of Applied Science and Engineering at the University of Pennsylvania.
According to Jeongyun Seo, because it can simulate the functions of the human eye, it can replace animal or human models for laboratory research. “Our eye-on-a-chip is focused on solving one of the most critical issues in health research: There is no effective preclinical model for disease modeling.†he said. “Our device can be used in many industries. , including drug development, toxicity screening of consumer products, etc.
In this project, the team collaborated with the laboratory's bioengineering expert Dan Huh, who has been working on the development of synthetic alternatives to biological systems, namely "organ-on-a-chip" ". Although Huh had previously developed other organ-on-a-chips, this time adding eye-on-a-chip to a blinking 3D printing eyelid was a pioneering effort. This eyelid is not designed for fun, it is said that it can be used to accurately simulate dry eyes in future projects.
However, unfortunately, although Penn State's eye-on-a-chip project was very exciting, it was still robbed of the university inventor's competition by Harvard's bioprinting organization project. The inventor of the latter was David Kolesky, a doctoral student in bioengineering at Harvard. He won the first prize with his 3D bioprinted vascularized human tissue and won a prize of US$15,000. It is understood that although many people have already successfully printed out human tissues in 3D, the uniqueness of Kolesky's 3D printing organization lies in its ability to maintain the activity of blood vessels for a long period of time. The breakthrough significance of this is self-evident. Yu's.
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